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. 2013 Aug 27;18(9):10378–10396. doi: 10.3390/molecules180910378

Table 5.

In vitro antifungal activity of synthesized guanidines and standard drug.

Compound Mean Values of Percent Growth Inhibition
A. flavus A. niger F. solani M. species A. fumagatus
1 10 ± 1.5 12.5 ± 2.0 20 ± 1.0 --- 47.5 ± 1.5
2 --- 72.5 ± 1.5 62.5 ± 2.5 --- 5 ± 0
3 --- 2.5 ± 1.5 20 ± 2.0 --- ---
4 --- 79 ± 1.0 32.5 ± 1.5 25 ± 1.0 ---
5 --- 66.5 ± 1.5 65.3 ± 1.7 --- 42.5 ± 2.4
6 --- 72.5 ± 0.5 62.5 ± 0.5 5 ± 0.5 55 ± 1.0
7 --- 70 ± 2.0 --- 50 ± 1.0 5 ± 1.0
8 64.5 ± 1.5 42.5 ± 2.5 62.5 ± 1.5 40 ± 2 20 ± 0.5
9 --- 32.5 ± 0.5 40 ± 2 12.5 ± 0.5 12.5 ± 0.5
10 --- 27.5 ± 0.5 47.5 ± 1.5 --- 20 ± 1
11 --- --- 25 ± 1.0 --- 30 ± 2
12 --- --- 39.5 ± 1.5 --- 10 ± 0
Terbinafine 100 100 100 100 100
Vehicle control --- --- --- --- ---

(a) --- Shows no activity; (b) In vitro agar tube dilution method; (c) concentration: 12 mg/mL of DMSO.