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. 2013 Jan 25;18(2):1582–1601. doi: 10.3390/molecules18021582

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© 2013 by the authors;

licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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The apparent permeability coefficient (Papp) (upper panel) and the transport percentage (lower panel) of each compound in EM of BPR in the secretory (B–A) direction (□) and in the absorptive (A–B) direction (⬛), and the efflux ratio (□). The structures and names of compounds 1–6 are referred to Figure 2. ^* Papp value of each tested compound in the secretory (B–A) direction significantly greater compared with Papp value in the absorptive (A–B) direction (p < 0.05). ^# Transport of each compound in EM of BPR in the secretory (B–A) direction significantly greater compared with in the absorptive (A–B) direction (p < 0.05).