Table 2.

Cytotoxicity of compounds 1–10 against seven human tumor cell lines (IC₅₀, μM) ^a.

Compound	Cell lines
	A-549	BGC-823	HepG2	HL-60	MCF-7	SMMC-7721	W480
1	10.3	11.3	9.2	12.0	10.7	23.7	28.0
2	52.7	61.8	49.0	59.4	54.3	59.7	59.5
3	44.1	40.8	30.4	39.6	36.8	47.0	40.1
4	-	-	-	-	-	-	94.9
5	97.4	-	-	-	-	92.1	-
6	13.0	12.9	10.8	12.3	11.3	24.9	29.9
7	49.1	53.2	43.6	48.2	46.7	49.4	52.7
8	47.8	51.5	44.8	50.7	48.9	53.2	51.4
9	61.3	67.1	58.3	71.8	64.2	66.2	62.1
10	16.1	15.7	14.8	17.2	14.7	31.2	35.5
Doxorubicin	18.3	14.7	22.0	31.7	24.9	35.4	15.9

^a Doxorubicin activities are expressed as IC₅₀ values in nM, and those of compounds 1–8 are expressed as IC₅₀ values in μM. (-) IC₅₀ > 100 μM.