Table 3.
Effect of aqueous extracts of Syzygium jambos and Solanum guaraniticum on lipid peroxidation level before and after sodium nitroprusside (SNP) incubation of rat homogenates.
| Treatments | Liver | Inhibition (%) | Brain | Inhibition (%) | Kidney | Inhibition (%) |
|---|---|---|---|---|---|---|
| Control | 2.23 ± 0.54 | ------- | 3.36 ± 0.93 | ------- | 1.62 ± 0.57 | ------- |
| Gallic acid 25 µg/mL | 1.26 ± 0.42 | 43.49 | 1.57 ± 0.51 | 53.27 | 1.29 ± 0.13 | 20.37 |
| Syzygium jambos 100 µg/mL | 1.98 ± 0.52 | 11.21 | 1.53 ± 0.18 * | 54.46 | 0.93 ± 0.25 | 42.59 |
| Syzygium jambos 250 µg/mL | 2.01 ± 0.51 | 9.86 | 1.19 ± 0.26 ** | 64.58 | 0.73 ± 0.18 | 54.93 |
| Solanum guaraniticum 500 µg/mL | 2.36 ± 0.53 | ------- | 1.49 ± 0.26 * | 55.65 | 0.81 ± 0.15 | 50.00 |
| Solanum guaraniticum 1000 µg/mL | 2.41 ± 0.40 | ------- | 1.89 ± 0.35 * | 43.75 | 0.84 ± 0.14 | 48.14 |
| Induced (SNP) | 10.81 ± 1.45 *** | ------- | 30.61 ± 3.41 *** | ------- | 4.78 ± 1.47 * | ------- |
| Gallic acid 25 µg/mL | 1.08 ± 0.09 ### | 90.00 | 27.88 ± 1.15 | 8.91 | 1.30 ± 0.22 ### | 74.26 |
| Syzygium jambos 100 µg/mL + SNP | 2.39 ± 0.51 ### | 77.89 | 2.97 ± 0.61 ### | 90.29 | 1.09 ± 0.30 ## | 77.19 |
| Syzygium jambos 250 µg/mL + SNP | 2.33 ± 0.47 ### | 78.44 | 1.95 ± 0.78 ### | 93.62 | 0.86 ± 0.10 ## | 82.00 |
| Solanum guaraniticum 500 µg/mL + SNP | 2.58 ± 0.65 ### | 76.13 | 1.86 ± 0.80 ### | 93.92 | 1.00 ± 0.20 ## | 79.07 |
| Solanum guaraniticum 1000 µg/mL + SNP | 2.75 ± 0.59 ## | 74.56 | 2.77 ± 0.74 ### | 90.95 | 1.18 ± 0.17 ## | 75.31 |
Data are reported as mean ± SEM (n = 6) and assessed by one way ANOVA followed by Duncan Multiple Comparison post hoc test. Results are presented as nmol MDA (malondialdehyde)/mg protein. (*), (**) and (***) denotes p < 0.05, p < 0.001 and p < 0.0001, respectively, as compared to the respective control samples. (#), (##) and (###) denotes p < 0.05, p < 0.001 and p < 0.0001, respectively, as compared to the respective induced samples.