Scheme 1.
Synthesis of [18F]1 and [18F]2.
Reagents and conditions: (a) [18F]KF, K222, K2CO3, DMF, 120 °C; (b) different conditions, optimized: Pd2(dba)3/P(o-tolyl)3/CuI, DMF-toluene, 65 °C, 20 min.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.