Skip to main content
. 2013 Sep 17;18(9):11537–11552. doi: 10.3390/molecules180911537

Figure 1.

Figure 1

Biotinylated G4 PAMAM dendrimers induce toxicity in the in vitro BBB model at the 48 h time point. There was no notable difference between the non-biotinylated dendrimers and cells treated with phosphate buffered saline (PBS; negative control) or sodium azide (positive control). Ryan’s (R-E-G-W-Q) post-hoc analyses revealed the following differences: * p < 0.05 when compared to PBS controls; ** p < 0.05 when compared to 1.5 μg/mL biotinylated dendrimers. All of the biotinylated dendrimers except 0.06 µg/mL were toxic when compared to PBS, and none differed from sodium azide, indicating cell toxicity. Bars 1–4 represent non-biotinylated dendrimers and bars 5–8 represent biotinylated dendrimers. Values represent means ± SEM.