Table 1.
Building block | Resulting [18F]fluoropeptide | Yield [%] | Purity [%] |
---|---|---|---|
[18F]2a | (18F-alkyne, n = 1)-YGGFL [18F]3a | 54 | 95 |
[18F]2b | (18F-alkyne, n = 2)-YGGFL [18F]3b | 97 | 98 |
[18F]2c | (18F-alkyne, n = 3)-YGGFL [18F]3c | 62 | 99 |
[18F]2b | AGDLHVLR-Ebes-Lys-(18F-alkyne, n = 2) [18F]4 | 97 | 81 |
[18F]2b | (18F-alkyne, n = 2)-AGDLHVLR [18F]5 | 99 | 87 |