Skip to main content
. 2013 May 16;18(5):5706–5722. doi: 10.3390/molecules18055706

Table 1.

BACE1 inhibitory activities of compounds 12–21. Inline graphic

Comp. R1 Inhibition ratio (100 μM) IC50 (μM)
5 H 77.00 ND a
12 graphic file with name molecules-18-05706-i002.jpg 40.69 ND
13 graphic file with name molecules-18-05706-i003.jpg 85.24 ND
14 graphic file with name molecules-18-05706-i004.jpg 58.75 ND
15 graphic file with name molecules-18-05706-i005.jpg 52.38 ND
16 graphic file with name molecules-18-05706-i006.jpg 66.51 ND
17 graphic file with name molecules-18-05706-i007.jpg 100 8.750 ± 1.075
18 graphic file with name molecules-18-05706-i008.jpg 35.3 ND
19 graphic file with name molecules-18-05706-i009.jpg 100 1.010 ± 0.091
20 graphic file with name molecules-18-05706-i010.jpg 46.8 ND
21 graphic file with name molecules-18-05706-i011.jpg 92.2 1.720 ± 0.210

a ND means not determined.