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Synthesis of functionalized N-acylhydrazone derivatives 1, 2a–d and 3a.
Reagents and conditions: (a) NH2NH2.H2O, 55–80 °C, 2–8 h, 79%–95%; (b) 4-(dimethylamino)benzaldehyde, catalytic HCl, EtOH, rt, 85%–99%; (c) CH3I, K2CO3, acetone, 43 °C, 24 h, 77%.
