Table 1.

Synthesis of N-acylhydrazone and N-methyl-N-acylhydrazone derivatives 1–3.

Compound	X	R1	R3	Yield (%) a,b	Ratio a:b
1	N	CH3	H	66	2:1
2a	N	H	H	21	4:1
2b	N	CH2CH3	H	49	1.7:1
2c	C	CH3	H	81	5:1
2d	C	H	H	84	c
3a	N	CH3	CH3	51	c

^a Global yield; ^b The analytical results for C, H and N were within 0.4% of the calculated values; ^b Ratio obtained by signal integration of the duplicate N=CH peaks in the ¹H-NMR spectra; ^c Only one signal is present.