Figure 1.

B16 melanoma cells were sensitive to aconitine. (A) Chemical structure of aconitine; (B) B16, B16F1 and B16F10 cells were treated with different concentration of aconitine ranging from 1.6 to 100 µg/mL for 48 h. Cell viability was determined by WST-1 method. Data were presented as means ± SEM from three separate experiments.