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Bioactive indolocarbazole (ICP-125).
Reagents and conditions: (a) NaH, DMF; (b) NaH, THF or MeI; (c) (COCl)2, CH2Cl2 or Et3N, CH2Cl2, 1-methylindole-3-acetic acid; (d) HMDS, MeOH, DMF, 99%; (e) Pd (O2CCF3)2, DMF, 94%; (f) 1M HCl (Et2O), MeOH, 98%.
