Figure 31.
2-Phenylindole-3-carbaldehydes derivatives as anticancer agents.
Reagent and conditions: (a) xylene, N,N-dimethylaniline, 170 °C; (b) POCl3, DMF, 15–70 °C, 3 h; (c) MeNH2, EtOH, 40 °C, 16 h; (d) H3NOH+Cl-, H2O/EtOH, NaOAc, reflux, 3 h.
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