Figure 6.
(A) synthesis of azide modified Pam2Cys via four steps: (i) piperidine, dichloromethane; (ii) imidazole-1-sulfonyl azide, potassium carbonate, methanol; (iii) palmatic acid (Pam), diisopropylcarboiimide, dimethylaminopyridine, tetrahydrofuran; (iv) trifluoroacetic acid; (B) CuAAC reaction of Pam2Cys construct.