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. 2013 Jun 21;18(6):7323–7335. doi: 10.3390/molecules18067323

Table 2.

The dosage regimens of Epimedium sagittatum (Sieb. et Zucc.) Maxim extract and sildenafil administration a.

Treatment group Dose of oral Epimedium sagittatum (Sieb. et Zucc.) Maxim extract b No. of herbal doses Sildenafil dose
1 c None 0 10 mg/kg
2 1 g/kg/day, 2h before sildenafil administration 1 10 mg/kg
3 1 g/kg/day 3 10 mg/kg
4 1 g/kg/day 3 30 mg/kg
5 2 g/kg/day 3 10 mg/kg
6 2 g/kg/day 3 30 mg/kg

a Each group contained six rats. bEpimedium sagittatum (Sieb. et Zucc.) Maxim extract was suspended in 2% carboxymethyl cellulose (1 g/mL). c Group 1 received vehicle (2% carboxymethyl cellulose, 1 g/mL) for 3 days as the control group