Table 2.
Treatment group | Dose of oral Epimedium sagittatum (Sieb. et Zucc.) Maxim extract b | No. of herbal doses | Sildenafil dose |
---|---|---|---|
1 c | None | 0 | 10 mg/kg |
2 | 1 g/kg/day, 2h before sildenafil administration | 1 | 10 mg/kg |
3 | 1 g/kg/day | 3 | 10 mg/kg |
4 | 1 g/kg/day | 3 | 30 mg/kg |
5 | 2 g/kg/day | 3 | 10 mg/kg |
6 | 2 g/kg/day | 3 | 30 mg/kg |
a Each group contained six rats. bEpimedium sagittatum (Sieb. et Zucc.) Maxim extract was suspended in 2% carboxymethyl cellulose (1 g/mL). c Group 1 received vehicle (2% carboxymethyl cellulose, 1 g/mL) for 3 days as the control group