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. 2013 May 17;18(5):5858–5890. doi: 10.3390/molecules18055858

Figure 7.

Figure 7

Pharmacokinetics of AuNPs (a–d) and iodine contrast agent (e–h) in mice. (a,e) Before injection. (b,f) 2 min after injection; (c,g) 10 min after injection; (d,h) 60 min after injection. The AuNPs show low liver and spleen uptake as well as clearance via kidneys and bladder (b–d). At 60 min (d), the contrast in the Au-injected mouse is similar to the uninjected mouse (a), indicating efficient clearance. A Lorad Medical Systems mammography unit (Hologic, Inc., Danbury, CT, USA; model XDA101827) is used with 8 mAs exposures (0.4 s at 22 kVp). Kodak Min-R2000 mammography film, 18 cm × 24 cm (Eastman Kodak, Rochester, NY, USA) is used [50]. Adapted by permission from The British Institute of Radiology.