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Schematic of biological processes and associated biological targets involved in the initiation, progression and complication of atherosclerosis. MR contrast agents have been shown useful for imaging of highly abundant proteins or cells such as collagen, elastin, fibrin, macrophages or VCAM-1 while PET tracer may be advantageous for visualization of low abundance targets such as MMPs or integrins. MR: magnetic resonance, PET: positron emission tomography, MMP: matrix metalloproteinase.
