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. 2012 Dec 28;18(1):398–407. doi: 10.3390/molecules18010398

Table 1.

Optimization of the indium-mediated dehalogenation reaction a.

graphic file with name molecules-18-00398-i039.jpg
Entry Solvent X Temperature (°C) Yield b (%) 2 Recovery b (%) 1
1 H2O Br rt - >99
2 H2O Br 100 - >99
3 THF Br rt - >99
4 THF Br 65 - >99
5 THF/H2O Br rt - >99
6 THF/H2O Br 65 - >99
7 TBAF Br 95 - >99
8 [bmim]Cl Br 95 70 30
9 [bmim]Cl Cl 95 60 40
10 [bmim]Cl I 95 3 97
11 [bmim]Br Br 95 >99 -
12 [bmim]Br Cl 95 >99 -
13 [bmim]Br I 95 >99 -
14 [(d3)-bmim]Br Br 95 >99 c -
15 [bmim]BF4 Br 95 - >99
16 [bmim]PF6 Br 95 - >99
17 [bmpy]F3CSO3 Br 95 - >99

a In (1 equiv.), in IL (2 equiv.), 14 h; b Values of 1 and 2 were determined by GC-MS; c2H-benzene was obtained.