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. 2013 Feb 25;18(3):2483–2500. doi: 10.3390/molecules18032483

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© 2013 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Suppressive effects of (A) ICAM-1 expression, (B) CCL5 and (C) IL-6 release of IL-33-activated human basophilic KU812 cells treated with dexamethasone (0.01 μg/mL) with or without GA (10 μg/mL) together. (A) Surface expressions of ICAM-1 on 5,000 KU812 cells are expressed as the mean plus SEM of MFI and normalized by subtracting appropriate isotypic control of three independent experiments. (B, C) Release of CCL5 and IL-6 in culture supernatants was determined by CBA. * p < 0.05, ** p < 0.005, *** p < 0.001. D: Dexamethasone 0.01 μg/mL, DMSO: dimethyl sulfoxide 0.2% (vol/vol), GA10: GA 10 μg/mL, GA100: GA 100 μg/mL.