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Main pharmacokinetic parameters of QGR in rats determined after intravenous and oral administration (n = 3, mean ± SD).
| PK parameters | Unit | Intravenous | Oral |
|---|---|---|---|
| t1/2 | min | 118.89 ± 5.65 | 236.87 ± 28.59 |
| AUC(0→t) | μg/mL × min | 1,775.96 ± 36.92 | 120.81 ± 11.38 |
| AUC(0→∞) | μg/mL × min | 1,790.24 ± 37.53 | 122.14 ± 16.15 |
| Tmax | min | - | 20 |
| Cmax | ng/mL | - | 495.69 ± 58.36 |
| F | % | - | 3.41 ± 1.21 |
