Table 9.

SUMMARY: Antifungal chemosensitization of OG or 2,3-DHBA (mM) to PCS (μg/mL) tested against Cryptococcus or Candida strains determined by EUCAST-based microdilution bioassays. Data shown are mean values derived from Table 5, Table 6, Table 7, Table 8. ^a

	Compounds	MIC	MIC	FICI	MFC	MFC	FFCI
		alone	combined		alone	combined
Cryptococcus	OG	0.04	0.01	0.3	0.04	0.01	0.3
	PCS	18.2	1.3		32.0	2.6
Candida	OG	0.07	0.05	1.2	0.1	0.08	1.5
	PCS	32.0	14.8		32.0	21.9
Cryptococcus	2,3-DHBA	0.2	0.05	0.4	1.5	0.8	0.9
	PCS	18.2	1.9		32.0	11.6
Candida	2,3-DHBA	0.3	0.2	1.1	6.8	6.8	2.0
	PCS	32.0	15.3		32.0	32.0

^a Synergistic FICIs and FFCI are indicated in bold.