Figure 3.

Effect of the iridoids isolated from the aerial parts of Castilleja tenuiflora on TPA-induced mouse ear edema. Groups of mice (n = 5) were treated at 0.1 mg/ear. The animals were killed four hours after the induction of inflammation. A punch biopsy was performed on each ear. The percentage of edema inhibition was calculated. The data are expressed as the means ± SEM. The differences between the control (indomethacin) and the treated groups with * p < 0.005 and ** p < 0.01 were considered significantly different compared to the control.