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. 2013 Sep 2;18(9):10599–10608. doi: 10.3390/molecules180910599

Table 3.

Antiprotozoal activity of G. mangostana extracts and α-mangostin.

Sample P. falciparum L. infantum T. cruzi T. brucei MRC-5
IC50 SI IC50 SI IC50 SI IC50 SI IC50
Dichloromethane extract 2.7 µg 3.5 7.5 µg 3.5 7.6 µg 1.2 0.5 µg 18.8 9.4 µg
Ethyl acetate extract 40.3 µg >1.6 >64 µg 1 34.6 µg 1.9 56.4 µg 1.1 >64 µg
α-Mangostin 2.2 µM 3.4 8 µM <1 8.9 µM <1 7.9 µM <1 7.5 µM