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. 2013 Jan 11;18(1):832–844. doi: 10.3390/molecules18010832

Table 1.

Antibacterial activity of the synthesized compounds: Agar diffusion method.

Compound No. Gram positive Gram negative
Staphylococcus aureus Bacillus cereus Serratia marcesens Proteus mirabilis
3 ++ ++ ++ ++
5 - - + +
7 ++ ++ + +
9a + + + +
9b + - + +
9c + + - -
11 + + + +
12a +++ +++ +++ +++
12b ++ +++ ++ ++
12c ++ ++ ++ ++
12d +++ ++ + ++
13 + + + +
16 ++ ++ +++ +++
17 ++ +++ +++ ++
18a + + +++ +
18b ++ ++ +++ +++

The width of the zone of inhibition indicates the potency of antibacterial activity; (-) no antibacterial activity; (+) mild activity with the diameter of the zones equal to 0.5–0.8 cm, (++) moderate activity with the diameter of the zones equal to 1.1–1.2 cm; (+++) marked high activity with the diameter of the zones equal to 1.8–2.0 cm.