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Effect of PF2401-SF on pro-apoptotic and anti-apoptotic proteins. Time-dependent downregulation of Bcl2 and upregulation of Bax was found in t-HSC/Cl-6 cells treated with 20 µg/mL PF2401-SF and analyzed by western blot. Regulation of these mitochondrial proteins correlates with apoptosis induction in vitro.
