Figure 3.

3D representations of the docking poses of (A) ombuin (9) (brown) and (B) quercetin (12) (blue-green) in complex with the human M₁ mAChR model obtained from induced-fit docking using Glide v5.7 and Prime v3.0 (Schrödinger LLC) with side views and top views (from the extracellular surface) depicted in the left hand and right hand panels, respectively. For the purpose of clarity, only D105 and W378 from among the active site residues are depicted in stick representation and some of the transmembrane helices are not shown.