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. 2014 Oct 29;19(11):17435–17463. doi: 10.3390/molecules191117435

Scheme 34.

Buchwald-Hartwig amination of quinazolin-4(3H)-one 102.

Scheme 34

Reagents and conditions: (i) morpholine or 1-(2-fluorophenyl)piperizine, Pd(OAc)2, t-BuOK, toluene, 100 °C, 20 h.