| R | X | EGFR TK, IC50 (nM) | |
|---|---|---|---|
| 62a | -Me | -(CH2)2- | 4 |
| 62b | -Me | -C(Me)N(Et2) | 30 |
| 62c | -Me | 0 | 15 |
| 62d | -Et | -(CH2)2- | 5 |
| 62e | -Et | -(CH2)3- | 140 |
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