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The Effects of DME on the mitochondrial membrane potential of L. amazonensis promastigotes. (A) Flow cytometry overlay histograms of the controls and DME-treated cells and stained with Rho 123. (B) Confocal image of the control and treated-cells. All control cells presented intense Rho123 labeling and preserved morphology. Cells treated with 2 × IC50 displaying a vanished fluorescence and drastic morphological changes.
