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The effect of eurycomanone and eurycomanol on K562 and Jurkat cell proliferation. IC50 values were determined using Prism 6.0 (GraphPad), based on leukemia cell proliferation rates during 84 h by using video microscopy.
| Cells | Compound | 8 h | 24 h | 48 h | 72 h |
|---|---|---|---|---|---|
| K562 | Eurycomanone | >150 µM | >150 µM | >150 µM | 14.2 µM |
| Eurycomanol | >200 µM | >200 µM | >200 µM | 143.8 µM | |
| Jurkat | Eurycomanone | >150 µM | >150 µM | 9.58 µM | 5.89 µM |
| Eurycomanol | >150 µM | >150 µM | 102.1 µM | 93.9 µM |
