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. 2014 Jul 17;19(7):10455–10472. doi: 10.3390/molecules190710455

Table 4.

Kinetics of NOTA-PEGn-RM26, (n = 2, 3, 4 and 6) binding to living PC-3 cells.

PEG2 PEG3 PEG4 PEG6
Association rate, ka, M−1 s−1 (2.9 ± 0.3) × 105 (8 ± 4) × 105 (5 ± 3) × 105 (6 ± 5) × 105
Dissociation rate, kd, s−1 (11.2 ± 0.0) × 10−6 (2.7 ± 0.2) × 10−6 (2.5 ± 0.0) × 10−6 (7 ± 3) × 10−6
KD, pM 23 ± 13 5 ± 3 8 ± 5 18 ± 8