Table 5.
Biological properties associated with the triterpenes with a focus on their potential chemotherapeutic applications.
No. | Activity | Ref. |
---|---|---|
1 | Antisweet activity Glucose uptake in rat small intestinal fragment Increase of serum glucose level in oral glucose-loaded rats Anti-hyperglycemic activity |
[31,35,38] [37,38] [46,47] [38] |
2 | Antisweet activity Glucose uptake in rat small intestinal fragment Increase of serum glucose level in oral glucose-loaded rats Anti-hyperglycemic activity |
[31,35,38] [37,38] [46,47] [38] |
3 | Antisweet activity Glucose uptake in rat small intestinal fragment Increase of serum glucose level in oral glucose-loaded rats Anti-hyperglycemic activity |
[30,31,35,38] [37,38] [46,47] [38] |
4 | Antisweet activity Glucose uptake in rat small intestinal fragment Increase of serum glucose level in oral glucose-loaded rats Anti-hyperglycemic activity Gut glycosidase inhibition |
[30,31,35,38] [37,38] [46,47] [38,65] [38] |
5 | Antisweet activity Increase of serum glucose level in oral glucose-loaded rats Anti-hyperglycemic activity Glucose uptake in rat small intestinal fragment |
[32,38] [46,47,65] [38] [38] |
6 | Antisweet activity | [32] |
7 | Antisweet activity Increase of serum glucose level in oral glucose-loaded rats |
[32] [46,47] |
10 | Antisweet activity | [35] |
11 | Antisweet activity | [35] |
12 | Antisweet activity | [35] |
13 | Antisweet activity | [35] |
14 | Antisweet activity | [35] |
15 | Antisweet activity | [36] |
16 | Antisweet activity | [36] |
17 | Antisweet activity | [36] |
18 | Antisweet activity | [36] |
19 | Antisweet activity | [31] |
Pharmacokinetic study: determination of gymnemagenin in rat plasma using HPLC-MS/MS | [66] | |
20 | Antisweet activity | [31] |
27 | Inhibition of the 11β-hydroxysteroid dehydrogenase type 1 | [63,66] |
28 | Hypoglycemic and antihyperglycemic effect in rats | [61] |
29 | Hypoglycemic and antihyperglycemic effect in rats | [61] |
30 | Hypoglycemic and antihyperglycemic effect in rats | [61] |
31 | Hypoglycemic and antihyperglycemic effect in rats | [61] |
32 | Increase of serum glucose level in oral glucose-loaded rats | [46,47] |
33 | Increase of serum glucose level in oral glucose-loaded rats | [46,47] |
34 | Glucose uptake in rat small intestinal fragment | [37] |
35 | Glucose uptake in rat small intestinal fragment | [37] |
36 | Glucose uptake in rat small intestinal fragment | [37] |
37 | Glucose uptake in rat small intestinal fragment | [37] |
39 | Antisweet activity | [34] |
40 | Antisweet activity Glucose uptake in rat small intestinal fragment |
[34] [46,47] |
41 | Antisweet activity | [34] |
42 | Antisweet activity Glucose uptake in rat small intestinal fragment |
[34] [46,47] |
43 | Antisweet activity Glucose uptake in rat small intestinal fragment |
[34] [37,47,59] |
44 | Inhibitory effects on human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT15) in vitro using the sulforhodamine B (SRB) assay | [55] |
46 | In vivo antitumor-promoting activity in mouse skin tumor | [50] |
Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol 13-acetate | [48,49] | |
Inhibition of phospholipid synthesis by 12-O-tetradecanoylphorbol-13-acetate | [67] | |
In vitro in human uterus cancer cells | ||
Anti-inflammatory activity and also to inhibit liver carcinogenesis and tumor growth | [51] |