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The effect of PD on the PI3K/Akt signaling pathway in U251 cells. U251 cells were treated with 0, 16.3, 40.8, 81.6 and 163.2 μM of PD for 48 h. Then the expressions of p-AKT and AKT were evaluated by western blot assay. Each value is presented as mean ± SD (n = 3). * p < 0.05 compared with 0 μM PD; ** p < 0.01 compared with 0 μM PD.
