Figure 5.

Dose-dependent effects of the phenolics 1–3, 7 on the formation of mineralized nodules in a 12-well plate fixed on Day 20 and stained by alizarin red. (A) Cells were treated with the phenolics 1–3, 7 at concentrations of 3.125, 6.25, 12.5, 25, 50 and 0 µg/mL (from a to f) on day 20; and (B) Dose-dependent effects of the phenolics 1–3, 7 on the area of mineralized bone nodules stained by alizarin red.

Note: * p ˂ 0.05 vs. negative control.