Table 2.

Protective effects of the phenolics 1–3, 7 on H₂O₂-induced cell injury in rat osteoblastic cells. Rat osteoblast cells were cultured in the presence of 100 μM H₂O₂ with or without treatment of the phenolics 1–3, 7 different concentrations. (A) The cell viability, and (B) the cell apoptosis, were assessed by MTT assay and flow cytometric analysis, respectively.

Concentrations (μg/mL)	(A) Cell Viability (%)
	1	2	3	7	Positive Control
0	211.23 ± 19.57 *	205.92 ± 20.41 *	211.45 ± 21.50 *	197.99 ± 18.51 *	210.12 ± 20.51 *
100 μM H2O2	102.43 ± 8.34	103.66 ± 9.80	103.99 ± 8.08	102.50 ± 10.50	102.50 ± 9.65
100 μM H2O2 + 3.125	127.43 ± 6.34	113.66 ± 10.48	123.99 ± 10.09	106.81 ± 10.40	131.81 ± 12.40
100 μM H2O2 + 6.25	131.32 ± 11.57 *	119.91 ± 10.50	126.02 ± 11.26	113.94 ± 11.33	163.94 ± 14.35 *
100 μM H2O2 + 12.5	144.36 ± 18.83 *	145.79 ± 12.61 *	136.81 ± 13.33 *	124.09 ± 12.64 *	234.06 ± 21.63 *
100 μM H2O2 + 25	198.44 ± 16.85 *	154.01 ± 14.94 *	188.02 ± 28.01 *	134.24 ± 24.61 *	499.24 ± 54.60 *
100 μM H2O2 + 50	319.46 ± 23.20 *	212.96 ± 19.07 *	288.29 ± 22.14 *	145.08 ± 16.06 *	766.08 ± 79.15 *
Concentrations (μg/mL)	(B) Cell Apoptosis (%)
	1	2	3	7	Positive Control
0	2.50 ± 0.70 *	2.55 ± 0.30 *	2.40 ± 0.21 *	2.04 ± 0.24 *	2.35 ± 0.17 *
100 μM H2O2	67.53 ± 4.56	66.87 ± 3.59	64.96 ± 6.73	68.67 ± 5.98	67.23 ± 4.39
100 μM H2O2 + 3.125	61.50 ± 5.73	62.50 ± 5.91	64.45 ± 3.34	66.50 ± 6.11	66.81 ± 6.41
100 μM H2O2 + 6.25	34.33 ± 3.44 *	57.94 ± 5.34 *	40.32 ± 3.57 *	60.29 ± 6.07	61.94 ± 5.33
100 μM H2O2 + 12.5	9.56 ± 0.99 *	46.09 ± 3.64 *	13.36 ± 2.83 *	55.13 ± 3.12 *	13.09 ± 1.63 *
100 μM H2O2 + 25	2.63 ± 0.19 *	24.16 ± 2.15 *	2.44 ± 0.19 *	45.70 ± 4.13 *	3.24 ± 0.20 *
100 μM H2O2 + 50	1.92 ± 0.21 *	10.68 ± 1.15 *	1.46 ± 0.20 *	23.89 ± 2.03 *	0.68 ± 0.06 *

Note: * p ˂ 0.05 vs. model group.