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. 2014 Dec 8;19(12):20557–20569. doi: 10.3390/molecules191220557

Figure 1.

Figure 1

Keratoconus. Left panel (a). Progressive and non-inflammatory disorder of the eye characterized by ectasia of the central and/or inferior portion of the cornea that induces irregular astigmatism and often myopia, resulting in mild to marked visual impairment. Keratoglobus. Right panel (b). Histopathologic and immunohistochemical abnormal features are similar in keratoglobus and keratoconus. In addition, the cornea in keratoglobus is diffusely thinned, often more markedly in the peripheral cornea, whereas in keratoconus the thinning is most prominent in the central cornea.