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Effect of WEAT on osteoclast function. Mature osteoclasts were plated on dentin slices, preincubated with or without WEAT for 3 h, and then treated with RANKL (100 ng/mL) for 16 h. (A) TRAP staining (upper panel) and resorbed pits by osteoclasts (down panel). Scale bars represent 100 μm. (B) The number of osteoclasts (Oc). (C) The total area of resorbed pits. ** p < 0.01 versus vehicle-treated control.
