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(a) Scheme of the DNA origami frame with a crossed geometry of attachment sites for the immobilization of loxP-containing DNA strands in antiparallel configuration and pathway of Cre-loxP recombination via an intermediate Holliday junction; (b) HSAFM images of the reaction, starting with the synaptic complex. Adapted with permission from Ref. [55]. Copyright 2013 American Chemical Society.
