Table 6.
Effects of resveratrol on lipid oxidation in in vivo studies.
| Authors | Experimental Design | Effects |
|---|---|---|
| Skeletal Muscle | ||
| Alberdi et al. (2013) [69] | Male Sprague-Dawley rats | ↑ TFAM and COX-II mRNA |
| 30 mg/kg body weight/day | ||
| 6 weeks | ||
| Lagouge et al. (2006) [72] | C57BL/6J mice | Larger mitochondrial structures ↑PGC-1α, TFAM and UCP3 mRNA |
| 400 mg/kg BW/day | ||
| 24, 48 h | ||
| Liver | ||
| Gómez-Zorita et al. (2012) [56] | Male Zucker rats | ↑Fatty acid oxidation |
| 15 mg/kg body weight/day | ||
| 6 weeks | ||
| Alberdi et al. (2013) [79] | Male Sprague-Dawley rats | ↓ACO, CPT1a |
| 30 mg/kg body weight/day | ||
| 6 weeks | ||
| Ahn et al. (2008) [80] | C57BL/6J mice | ↓Liver weight ↑PPARα gene expression |
| 10 mg/kg body weight/day | ||
| 8 weeks | ||
TFAM: Mitochondrial transcription factor A; COX-II: Cytochrome oxidase subunit II; PGC-1α: Proliferator-activated receptor-gamma coactivator 1α; UCP: Uncoupling protein; ACO: Acyl CoA oxidase; CPT: Carnitine palmitoyl transferase PPARα: Peroxisome proliferator-activated receptor alpha.