Table 2.

Cytotoxic activities of 1–7, and hirsutanol A in vitro. IC₅₀ values in µM ^a.

Cancer cell Lines	1	2	3	4	5	6	7	Hirsutanol A
Human nasopharyngeal carcinoma cell line CNE1	1.43	2.09	0.76	16.28	6.46	15.58	1.85	10.06
Human nasopharyngeal carcinoma cell line CNE2	0.73	1.21	0.54	9.04	4.51	9.77	1.81	12.70
Human nasopharyngeal carcinoma cell line SUNE1	2.23	2.76	2.30	24.06	8.78	11.36	4.41	3.53
Human nasopharyngeal carcinoma cell line HONE1	–	–	1.18	16.72	7.40	11.17	2.78	17.48
Human lung cancer cell line A549	–	–	1.97	20.17	–	15.92	3.79	12.05
Human lung cancer cell line GLC82	–	–	–	15.38	5.52	16.97	3.46	10.11
Human breast cancer cell line MCF-7	–	–	2.85	19.30	8.26	10.07	5.27	10.35
Human hepatic cancer cell line Bel–7402	–	–	3.32	16.73	7.78	11.38	3.66	24.80

^a – = not screened.