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Effects of methylpenicinoline (1) on COX-2 (A) and iNOS (B) expression in RAW264.7 macrophages stimulated with LPS. Cells were pre-treated for 30 min with indicated concentrations of 1 and then for 24 h with LPS (500 ng/mL). Western blot analyses (A,B) were performed as described in described in Section 3.7; representative blots of three independent experiments are shown. Data are the mean values of three experiments ± S.D. * p < 0.05 compared to the group treated with LPS alone.
