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. 2014 Mar 5;19(3):2877–2895. doi: 10.3390/molecules19032877

Table 3.

Summary of alternative approaches and treatment found to counteract DPN.

Kind of Therapy/ Genus/Species
Class of Compounds Subclass of Compound
Acupuncture
Electrotherapy
Oriental Chinese Medicine Astragalus Radix
Angelicae Sinensis Radix
Pheretima
Chuanxiong Rhizoma
Codonopsis Radix
Carthami Flos
Hirudo
Rehmanniae Radix
Spatholobi Caulis
Paeoniae Radix Rubra
Cyathulae Radix
Asari Radix and Rhizoma
Scolopendra
Astragaloside IV
(Radix Astragalus membranaceus Bunge)
Guineensine, extracted from Piper longum
Tang-Luo-Ning mainly contains three different traditional Chinese herbs: Huang Qi, Chishao and Salvia miltiorrhiza Bge. (Danshen)
Phenolic Compounds Allium cepa and Allium sativum
Momordica Charantia Linn
Chlorogenic Acid
Syringic Acid
Vanillic Acid
Ellagic and Gallic Acids
Hydroxytyrosol (Terminalia bellirica Roxb)
Cannabinoids Cannabis sativa
Alkaloids Cocaine (from the leaves of the Erythroxylum coca plant)
Morphine (extracted by “poppy pods”- Papaver somniferum-)
Papaverine
Serotonin (roots, leaves, fruits and seeds from at least 42 species, such as dates, papayas and bananas)
Caffeine (seeds, leaves, and fruit of some plants such as coffee and tea bush, as well as from kola nut, yerba maté, guarana berries, guayusa, and the yaupon holly),
Theobromine (the main alkaloid present in Theobroma cacao)
Vanilloids Capsaicin (component of chili peppers—Capsicum annuum)
Essential Fatty Acids Evening primrose oil, extracted from the seeds of Oenothera biennis