Figure 7.

Effects of pinocembrin on cell apoptosis in the penumbra cortex of the rats after subjected to 2 h of MCAO followed by 24 h reperfusion. (a) TUNEL staining was performed on the sections from the penumbra cortex (magnification: 200×). A: sham; B: I/R; C: I/R + pinocembrin 1 mg/kg; D: I/R + pinocembrin 3 mg/kg; E: I/R + pinocembrin 10 mg/kg; F: edaravone 3.5 mg/kg. (b) Quantification of the effect of pinocembrin on ratio of tunel positive cells. Data are expressed as means ± SD and analyzed by one-way ANOVA followed by Dunett’s test. n = 3. ^### P < 0.001 vs. I/R group, *** P < 0.001 vs. sham group.