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. 2014 Apr 17;19(4):4941–4955. doi: 10.3390/molecules19044941

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© 2014 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Flow cytometric analysis of the changes in the mitochondrial membrane potential (ΔΨ m) in MCF-7 cells treated with CPT6 for 48 h. A: (a) Control group; (b) treatment with 0.25 nM CPT6; (c) treatment with 0.5 nM CPT6; (d) treatment with 1 nM CPT6. B: Reduction in ΔΨ m in MCF-7 cells treated with CPT6. The data was obtained according to the percentage of cell number in Q4 quadrant which elicited strong fluorescence, resulting from three independent experiments (* p < 0.05, ** p < 0.01); p value compared with the control group (0 nM CPT6).