Table 1.
Structural and functional properties of several carnosinases.
| Full name | Organism | Tissue | FW (KDa) |
Activation | Optimal pH |
Main substrate | Main Inhibitors | |
|---|---|---|---|---|---|---|---|---|
| CN1 | Serum carnosinase | Homo sapiens | Brain, serum, liver | 56.8 | Cd2+ citrate |
7.5 | Carnosine | Phenantroline |
| CN2 | Cytosolic carnosinase | Homo sapiens | Ubiquitous | 52.9 | Mn2+ | 9.5 | Xaa-His | Bestatin |
| ANSN | Anserinase | Oncorhynchus mykiss | Brain, eyes | 55.0 | Co2+, Zn2+ | Anserine | Bestatin | |
| PepV | Peptidase V | Lactobacillus delbrueckii | Cytoplasm | 52.0 | Carnosine | Phenantroline EDTA |
||
| PepD | Peptidase D | E. Coli | Cytoplasm | 52.9 | Co2+ | 9.0 | Xaa-His | Metal chelators |