Table 1.
Correlations between total bile acid (TBA) concentrations and total cell count and differential cell counts of bronchoalveolar lavage fluid (BALF)
| Variable | CIPF WHWTs (n = 27) |
Healthy WHWTs (n = 13) |
CB (n = 13) |
BP (n = 11) |
IWHs (n = 8) |
EBP (n = 9) |
LD (n = 19) |
|---|---|---|---|---|---|---|---|
| RV (%) Median Range |
35 14‐69 |
54 33‐74 |
26 13‐48 |
54 33‐74 |
22 7.8‐45 |
27 12‐52 |
49a
26‐64 |
| TCC, n/μL Median |
860 | 360 | 350 | 220** | 175 | 620 | 1046 |
| Range | 220‐2600 | 270‐630 | 20‐1380 | 70‐3670 | 30‐470 | 100‐1920 | 60‐33 600 |
| r s | 0.30 | 0.12 | 0.17 | 0.82 | 0.41 | 0.64 | −0.02 |
| Mac, n/μL Median |
650* | 280 | 250 | 87 | 125 | 180 | 570 |
| Range | 156‐2340 | 190‐470 | 9.0‐560 | 31‐6130 | 7.0‐270 | 77‐880 | 45‐4900 |
| r s | 0.41 | 0.01 | 0.09 | 0.57 | 0.41 | 0.24 | −0.02 |
| Mac % Median |
77 | 79 | 71 | 48* | 65 | 46 | 55 |
| Range | 26‐96 | 69‐86 | 31‐95 | 3.0‐64 | 24‐79 | 18‐77 | 12‐91 |
| r s | 0.05 | −0.28 | 0.31 | −0.66 | −0.41 | −0.30 | −0.21 |
| Neu, n/μL Median |
52 | 16 | 24 | 30** | 6,2 | 48 | 106 |
| Range | 2.6‐370 | 3.0‐110 | 0.4‐78 | 5.0‐30 400 | 1.9‐20 | 1.4‐680 | 1.6‐26 900 |
| r s | 0.24 | 0.17 | −0.11 | 0.87 | 0.58 | 0.38 | −0.27 |
| Neu (%) Median |
6.4 | 4.1 | 4.2 | 12** | 4.6 | 5.7 | 9.5 |
| Range | 0.7‐38 | 1.0‐10 | 0.4‐52 | 3.4‐98 | 0.4‐16 | 1.0‐14 | 0.7‐87 |
| r s | 0.17 | 0.43 | 0.003 | 0.90 | 0.25 | −0.11 | −0.33 |
| Eos, n/μL Median |
1.2 | 1.8 | 9.0 | 9.1 | 1.4 | 310 | 37 |
| Range | 0.5‐22 | 0–12 | 0–110 | 0–260 | 0–17 | 17‐940 | 0‐1600 |
| r s | −0.038 | 0.08 | 0.31 | −0.21 | 0.43 | 0.62 | −0.006 |
| Eos (% Median) |
0.2 | 0.5 | 1.4 | 3.6** | 0.9 | 34 | 4.5 |
| Range | 0‐2.4 | 0‐6.0 | 0‐22 | 0–21 | 0–11 | 17‐69 | 0–62 |
| r s | −0.13 | −0.11 | 0.28 | −0.82 | 0.09 | 0.57 | −0.11 |
| Mast, n/μL Median |
4.8 | 0.8 | 3.0 | 0.0* | 1.3 | 9.7 | 2.3 |
| Range | 0–64 | 0‐3.0 | 0‐9.0 | 0‐7.3 | 0‐4.3 | 0‐36 | 0–38 |
| r s | 0.33 | 0.42 | 0.42 | −0.73 | 0.42 | 0.25 | 0.22 |
| Mast (%) Median |
0.70 | 0.20 | 1.0 | 0* | 0.4 | 0.70 | 0.50 |
| Range | 0‐2.5 | 0‐0.9 | 0‐2.6 | 0‐4.4 | 0‐2.4 | 0‐7.7 | 0‐3.0 |
| r s | 0.27 | 0.12 | 0.38 | −0.73 | 0.26 | 0 | 0.22 |
| Lymp n/μL Median |
60 | 56 | 34 | 25 | 41 | 74 | 112 |
| Range | 12‐340 | 40‐93 | 3.0‐710 | 0‐150 | 3.0‐190 | 4.0‐150 | 7.0‐2030 |
| r s | 0.14 | 0.064 | 0.31 | −0.19 | 0.41 | 0.35 | −0.06 |
| Lymp % Median |
7.4 | 15.7 | 9.7 | 20** | 21 | 11 | 8.3 |
| Range | 0.9‐30 | 10‐21 | 3.7‐52 | 0–30 | 10‐42 | 4.0‐16 | 1.0‐35 |
| r s | −0.14 | −0.11 | 0.051 | −0.85 | 0.58 | −0.18 | 0.013 |
Statistically significant difference * <.05 and ** <.01.
Abbreviations: BP, bacterial pneumonia; CB, chronic bronchitis; CIPF, canine idiopathic pulmonary fibrosis; EBP, eosinophilic bronchopneumopathy; Eos, Eosinophil; IWHs, Irish Wolfhounds; LD, laryngeal dysfunction; Lymp, Lymphocyte; Mac, Macrophage; Mast, Mast cell; Neu, Neutrophil; r s, Spearman's rank correlation coefficient; TCC, total cell count; RV, Recovered volume; WHWTs, West Highland White Terriers.
a
Data available only from 6 dogs.