Table 2.

Anti-proliferative effects of aporphine alkaloids on AGS and DU-145 cells.

Sample	IC50 (µM)
	AGS	DU-145
Liriodenine (1)	˃500	95.4 ± 0.4
Lysicamine (2)	˃500	˃500
(−)-Anonaine (3)	˃500	150.1 ± 0.3
(−)-Asimilobine (4)	˃500	˃500
(−)-Caaverine (5)	˃500	94.4 ± 0.1
(−)- N-Methylasimilobine (6)	˃500	˃500
(−)-Nuciferine (7)	˃500	218.4 ± 0.5
(−)-Nornuciferine (8)	˃500	˃500
(−)-Roemerine (9)	˃500	˃500
7-Hydroxydehydronuciferine (10)	62.9 ± 0.1	80.8 ± 0.2
Cepharadione B (11)	˃500	na

Data in the table are means ± S.D. of n = 3; na: no testing.