Table 2.
Differences between baseline and 12 ± 3 months
| Variable | Baseline | 12 ± 3 months | Interval difference | P* |
|---|---|---|---|---|
| kurtosis | 1.26 (0.41, 2.26) | 0.94 (0.01, 1.53) | −0.32 | 0.25 |
| skewness | 1.34 (1.07, 1.53) | 1.15 (0.87, 1.41) | −0.19 | 0.25 |
| MLD | − 777.92 (− 801.37, − 745.61) | − 764.76 (− 786.15, − 733.01) | −13.16 | 0.40 |
| HAA% | 14.42 (10.74, 17.79) | 15.19 (12.81, 20.45) | 0.77 | 0.40 |
| FA% | 24.68 (19.06, 32.00) | 26.69 (22.14, 33.97) | 2.01 | 0.68 |
| FVC% | 86 (75, 96) | 85 (76.5, 105.25) | −1 | 0.88 |
| DLCO% | 67 (56, 72.50) | 53 (40.75, 68.75) | −14 | 0.02 |
| GAP (points) | 3 (2.25, 4) | 3 (3, 4) | 0 | 0.21 |
Data are expressed as median (interquartile range)
aMLD Mean Lung Density, bHAA High attenuation areas, cFA Fibrotic Areas, dFVC Forced Vital Capacity, eDLCO Diffusing Capacity for carbon monoxide, fGAP Gender-Age-Physiology index, * Reported pwere adjusted with Holm’s correction