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. 2014 Nov 14;19(11):18721–18732. doi: 10.3390/molecules191118721

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© 2014 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Changes of MMP levels of MESR-incubated Ca9-22 oral cancer cells. Cells were incubated with MESR (0–2.5 mg/mL) for 24 h for flow cytometry analysis. The vertical lines in each plot dichotomised the MMP intensity scales into 50%/50% in reference to the left and right sides of control. The right side of MMP intensity was regarded as MMP-positive (%). (A) Typical MMP patterns of MESR-incubated Ca9-22 cells. (B) Statistics of relative MMP-positive intensity (%) in Figure 5A. All the MMP intensity data were normalized to control as 100% for the relative MMP (%) calculation. Data, means ± SDs (n = 3). ** p < 0.001 against control.