Table 1.

Antibacterial activity (MIC) of the synthesized pleuromutilin derivatives.

Comp.	MIC (μg/mL)
	MRSA	MRSE	S. aureus	S. epidermidis	E. coli	B. cereus
5a	32	64	32	32	≥128	16
5b	64	≥128	64	64	≥128	32
5c	32	32	16	32	64	4
6a	8	16	4	16	32	2
6b	32	32	32	32	64	16
6c	8	32	8	16	64	8
6d	0.5	4	0.5	2	32	0.25
Tiamulin	0.5	2	0.5	2	16	0.25